TirzaFit disposable pre-filled pen 40 mg / 3 ml (Tirzepatide INN)
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❄️ Temperature-controlled delivery (2–8°C) across the EU.
METABION TirzaFit 40 mg / 3 mL (purple edition) is a pre-filled multi-dose disposable pen delivering 13.33 mg/ml Tirzepatide INN. Tailored for patients initiating therapy, it provides exceptionally smooth dosing for the standard 2.5 mg and 5.0 mg titration protocols.
Tirzepatide is a first-in-class dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. By simultaneously activating both incretin pathways, it exerts synergistic metabolic control: promoting glucose-dependent insulin secretion from pancreatic beta cells, suppressing inappropriate glucagon release, slowing gastric motility, and stimulating central hypothalamic satiety circuits to curb appetite and enhance peripheral insulin sensitivity.
TirzaFit 40 mg pen. Subcutaneous administration once weekly according to clinical titration schedule.
To ensure gastrointestinal tolerability, Tirzepatide administration must follow a stepwise escalation protocol. Treatment initiates at a low starting dose of 2.5 mg subcutaneously once weekly for the initial 4 weeks (adaptation phase). The dose is then increased to 5.0 mg once weekly. Subsequent increments of 2.5 mg may occur at minimum 4-week intervals based on clinical assessment and tolerance, up to the maximum dose of 15.0 mg weekly.
| Active ingredient | Tirzepatide INN |
|---|---|
| Strength & Volume | 40 mg in 3 mL (13.33 mg/mL) |
| Excipients | Disodium phosphate, NaCl, HCl, WFI |
| Device | Pre-filled disposable pen |
| Brand | Metabion |
| Storage | 2°C to 8°C |
Store refrigerated at 2°C to 8°C (36°F to 46°F). Protect from direct light. Do not freeze. For pre-filled pens: once in use, the pen may be kept at room temperature (below 30°C / 86°F) for up to 21-28 days. For reconstituted vials: maintain in refrigerator at 2°C to 8°C and use sterile single-use syringes.
Tirzepatide is injected subcutaneously exactly once per week, at any time of day, with or without meals.
