Multi-dose disposable pen with tirzepatide 60 mg / 3 ml (dual GLP-1 / GIP incretin agonist)
In stock — dispatch within 48h
❄️ Temperature-controlled delivery (2–8°C) across the EU.
AFIRA Tirzepatide 60 mg / 3 ml is an ergonomic multi-dose disposable pen containing a high-concentration tirzepatide solution (20 mg/ml in a 3 ml pre-filled glass cartridge). Engineered with an intuitive dial-and-click dose selector, it enables micro-precise subcutaneous administration. The generous 60 mg total volume allows sustained treatment through progressive titration stages without frequent pen replacements.
Tirzepatide is a first-in-class dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. By simultaneously activating both incretin pathways, it exerts synergistic metabolic control: promoting glucose-dependent insulin secretion from pancreatic beta cells, suppressing inappropriate glucagon release, slowing gastric motility, and stimulating central hypothalamic satiety circuits to curb appetite and enhance peripheral insulin sensitivity.
The AFIRA pre-filled pen is immediately ready for use with no reconstitution required. Attach a sterile disposable needle, dial the required dose on the indicator window, and deliver the subcutaneous injection at a 90° angle into the abdomen, upper thigh, or outer arm, holding the push button for 5-10 seconds.
To ensure gastrointestinal tolerability, Tirzepatide administration must follow a stepwise escalation protocol. Treatment initiates at a low starting dose of 2.5 mg subcutaneously once weekly for the initial 4 weeks (adaptation phase). The dose is then increased to 5.0 mg once weekly. Subsequent increments of 2.5 mg may occur at minimum 4-week intervals based on clinical assessment and tolerance, up to the maximum dose of 15.0 mg weekly.
| Active substance | Tirzepatide (CAS 2023706-61-5) |
|---|---|
| Total dose | 60 mg |
| Cartridge volume | 3.0 mL (20 mg/mL) |
| Device type | Pre-filled multi-dose pen |
| Route of administration | Subcutaneous (SC) 90° |
| Manufacturer / Brand | Afira Biosystems |
| Storage | 2°C – 8°C (Do not freeze) |
Store refrigerated at 2°C to 8°C (36°F to 46°F). Protect from direct light. Do not freeze. For pre-filled pens: once in use, the pen may be kept at room temperature (below 30°C / 86°F) for up to 21-28 days. For reconstituted vials: maintain in refrigerator at 2°C to 8°C and use sterile single-use syringes.
The pen is compatible with standard universal screw-on insulin pen needles (e.g., 31G or 32G, lengths 4 mm, 5 mm, or 6 mm).
An in-use pen may be stored at room temperature below 30°C (86°F) or refrigerated at 2°C to 8°C for up to 28 days with the cap securely in place.
