Store at 2–8 °C. For professional use by qualified medical personnel only.
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Product overview
Coretox is a new-generation Medytox type A botulinum toxin formulated without complexing proteins. Removing unnecessary proteins reduces immunological load and the risk of resistance with repeated treatments while maintaining effective, natural-looking wrinkle reduction. An excellent choice for patients planning long-term treatment.
Protein-free formula (without complexing proteins)
Lower risk of resistance and antibody formation
No human albumin — stabilized with polysorbate
Ideal for long-term treatment
How it works
Type A botulinum toxin temporarily blocks nerve signals to the muscles. After administration, it inhibits the release of acetylcholine — the neurotransmitter responsible for muscle contraction.
Relaxing the treated muscles reduces the movements that cause expression lines, smooths the skin and gives the face a rested appearance. When administered correctly by trained personnel, the effect is local and does not spread throughout the body.
Composition
Core type A botulinum toxin (100 U)Pure neurotoxin without complexing proteins — lower risk of immunogenicity.
Polysorbate (stabilizer)Replaces human albumin — a formula free from blood-derived ingredients.
Sodium chlorideAdjusts the solution’s pH and tonicity.
Treatment areas
Face
Patients sensitive to complexing proteins
Glabellar lines, forehead and crow’s feet
Long-term and maintenance treatment
Body (therapeutic applications)
Areas affected by muscle spasticity
Upper limbs (post-stroke spasticity)
Excessive sweating of the underarms and palms
Preparation and reconstitution
The product is supplied as a fine powder that must be dissolved in saline before use. Correct preparation supports safe and effective administration.
Required materials
0.9% saline solution (NaCl)
Sterile 30G 0.5 cc insulin syringe
Latex gloves
Alcohol swabs
Preparation steps
1Remove the vial from the refrigerator and inspect it visually — it should be clear, with a small amount of white or pale-yellow powder.
2Draw the appropriate amount of saline into the syringe and inject it slowly into the vial.
3Gently rotate the vial to mix — do not shake vigorously.
4The solution should be clear and free of particles. Store at 2–8 °C and use within 24 hours.
Dilution table
0.9% NaCl added
Coretox 100 Units
Dose (U / 0.1 ml)
1,0 ml
→
10 U
2,0 ml
→
5 U
2,5 ml
→
4 U
4,0 ml
→
2,5 U
The powder is extremely fine, so the vial may appear empty — all units are present.
The manufacturer recommends use within 24 hours after dilution; studies indicate stability for up to 5 weeks when stored at 2–8 °C.
Treatment course
1treatment session for a visible result
3–4months of effect duration
3–6months until a maintenance treatment
4–6weeks
How quickly results appear
Initial effects are usually visible within a few days, with the full result developing over 4–6 weeks. Timing varies by individual and treatment area.
Aftercare
Do not massage or press the injection site for at least 24 hours.
Remain upright and do not lie down for 4–6 hours.
Avoid strenuous physical activity for 24–48 hours.
Avoid saunas, hot baths and sun exposure for at least 24 hours.
Postpone facial treatments such as peels and microdermabrasion for at least one week.
Mild redness or swelling usually resolves within a few days.
The product may be administered only by licensed medical personnel trained in botulinum toxin injections. Dose and technique depend on the treatment area and the patient’s individual condition.
Results — before and after
BEFOREAFTER
Images are for illustration. Results vary and depend on the administration technique.
What is included
1 vial of Coretox 100U (protein-free formula)
0.9% saline for dilution
Preparation instructions
Frequently asked questions
Coretox contains no complexing proteins, so less foreign protein enters the body, reducing the risk of an immune response.
Yes — the lower protein load limits antibody formation, which matters with repeated treatments.
Storage
Store unopened vials refrigerated at 2–8 °C.
Do not freeze.
After reconstitution, keep refrigerated and use within 24 hours.
Protect from light; do not use if the solution is discolored or contains particles.
For use by licensed medical personnel only. Incorrect storage or administration may affect product quality.